How often does CIN 2 become cancer?
However, it is estimated that 5% of CIN 2 and 12% of CIN 3 cases will progress to invasive cancer if untreated. In general, it takes 10 to 20 years for CIN to progress to cancer, allowing a significant time period for detection and treatment.
Can CIN 2 be cancer?
Moderate cervical lesions — formally known as cervical intra-epithelial neoplasia grade 2 (CIN2) — are abnormal cells on the surface of the cervix. CIN is notcervical cancer, but does have the potential to progress to cancer. However, in many cases these cells may also return to normal or remain unchanged.
Is CIN 2 low-grade?
Low-grade neoplasia (CIN 1) refers to dysplasia that involves about one-third of the thickness of the epithelium. CIN 2 refers to abnormal changes in about one-third to two-thirds of the epithelial layer. CIN 3 (the most severe form) describes a condition that affects more than two-thirds of the epithelium.
What does CIN 2 stand for in Pap smear results?
The grades of CIN are:5. CIN 1 (grade 1): Also called low-grade or mild dysplasia, there are slightly abnormal cells found on the cervix. CIN 2 (grade 2): Moderately abnormal cells have formed on the cervix.
How serious is CIN 2?
CIN 2 is not cancer, but may become cancer and spread to nearby normal tissue if not treated. Treatment for CIN 2 may include cryotherapy, laser therapy, loop electrosurgical procedure (LEEP), or cone biopsy to remove or destroy the abnormal tissue. CIN 2 is sometimes called high-grade or moderate dysplasia.
How fast does CIN 2 become cancerous?
The median time from CIN2/3 to cancer was estimated to be 23.5 years (95% confidence interval: 20.8, 26.6), and 1.6% of the lesions progressed to cancer within 10 years.
Will CIN2 go away?
In the majority of cases, moderate cervical dysplasia (also called cervical intraepithelial neoplasia 2, CIN2) will resolve itself, but some of these women will go on to develop cervical cancer. Women with moderate dysplasia may face a choice between undergoing prompt treatment, or short-term surveillance.
Can CIN2 come back?
Women treated for CIN2 or CIN3 retain an elevated risk of recurrence or even invasive cancer for years following treatment (2, 3). Thus, heightened surveillance has been the rule, with uncertainty as to whether (and when) a return to normal screening intervals can be safely permitted.
Is CIN2 contagious?
It is not contagious and cannot be passed on to other people. The cervix is the lower part of the uterus and is often called the ‘neck of the uterus. ‘ The uterus is a muscular, pear-shaped organ at the top of the vagina. The lining of the uterus is shed each month, and results in bleeding called a period.
How do I get rid of precancerous cells in my cervix?
Conization. Doctors remove a cone-shaped piece of tissue from the cervix in a procedure called conization. They may use conization to remove precancerous tissue high up in the cervical canal, along with a border of surrounding healthy tissue, to help ensure that all of the precancerous cells have been taken out.
What happens if you have precancerous cells in cervix?
Precancerous conditions of the cervix are changes to cervical cells that make them more likely to develop into cancer. These conditions are not yet cancer. But if they aren’t treated, there is a chance that these abnormal changes may become cervical cancer.
What happens if your colposcopy comes back abnormal?
You may need treatment if the results of your colposcopy show that there are abnormal cells in your cervix. The abnormal cells will be removed, which usually involves removing an area of the cervix about the size of a finger tip.