Is HSIL the same as carcinoma in situ?

Is HSIL a cancer?

HSIL is a squamous cell abnormality associated with human papillomavirus (HPV). Though not all HSIL will progress to cancer, HSIL is considered to be a precancerous lesion and therefore is usually treated aggressively.

Is HSIL carcinoma in situ?

HSIL, the entity in The Bethesda System for reporting of cervical carcinoma, therefore encompasses moderate dysplasia, severe dysplasia and carcinoma in situ.

What percentage of HSIL is cancer?

HSIL. CIN 2 or CIN 3 has been reported in at least 70 percent of women with cytology results of high-grade squamous intraepithelial lesions (HSIL), and 1 to 2 percent have invasive cancer.

How serious is HSIL?

High-Grade Squamous Intraepithelial Lesions (HSIL) means that there are moderately or severely abnormal cervical cells that could become cancer in the future if not treated. Your health care provider will likely ask you to come back for a colposcopy.

How often does HSIL turn into cancer?

If the abnormality spreads down into the layers of tissue below the skin, that is when it is considered anal cancer. It’s important to remember that very few areas of HSIL ever turn into anal cancer. It’s estimated that only 1 in 1000 high grade lesions turn into cancer each year.

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How serious is carcinoma in situ?

These in situ cells are not cancer, but they could become malignant. If they do this, they can start to invade other tissues. For this reason, a doctor will recommend treatment to remove the cells. This will reduce the risk of cancer developing later.

What stage is carcinoma in situ?

In general, carcinoma in situ is the earliest form of cancer, and is considered stage 0. An example of carcinoma in situ is ductal carcinoma in situ, or DCIS, which is considered an early form of breast cancer and occurs when abnormal cells form a breast’s milk duct.

What is the recommended treatment for carcinoma in situ?

Local treatment for DCIS usually involves breast-conserving therapy (BCT), which consists of lumpectomy (also called wide excision or partial mastectomy) followed in most cases by adjuvant radiation therapy (RT). Alternatively, mastectomy may be considered.

What is the treatment for high grade dysplasia?

Esophagectomy has traditionally been recommended for patients found to have high-grade dysplasia or early cancer. (See “Barrett’s esophagus: Surveillance and management”.) Endoscopic therapy has been proven to be a safe, effective, and less invasive alternative to surgery for treating such patients.