Which tumors are considered germ cell tumors?
The most common types of germ cell tumors include:
- Teratomas. Teratomas contain cells from the three germ layers: ectoderm, mesoderm, and endoderm. …
- Germinomas. Germinomas are malignant germ cell tumors. …
- Endodermal sinus tumor or yolk sac tumors. …
- Choriocarcinoma. …
- Embryonal carcinoma.
What is a seminoma tumor?
(SEH-mih-NOH-muh) A type of cancer that begins in germ cells in males. Germ cells are cells that form sperm in males or eggs in females. Seminomas occur most often in the testicle, but they may also occur in other areas of the body, such as the brain, chest, or abdomen. Seminomas tend to grow and spread slowly.
What type of cancer is seminoma?
Seminoma: This is a slow-growing form of testicular cancer found in men in their 40s and 50s. The cancer is in the testes, but it can spread to the lymph nodes. Lymph node involvement is either treated with radiotherapy or chemotherapy. Seminomas are very sensitive to radiation therapy.
Is Sertoli cell tumor a germ cell tumor?
They are very rare and generally peak between the ages of 35 and 50. They are typically well-differentiated, and may be misdiagnosed as seminomas as they often appear very similar. A tumor that produces both Sertoli cells and Leydig cells is known as a Sertoli-Leydig cell tumor.
|Sertoli cell tumour|
What is the survival rate of germ cell tumor?
The survival and cure rates also depend on several factors, including the stage of the disease. The cure rate for children with a stage I or stage II germ cell tumor is 90%. The cure rate for a stage III tumor is 87%. The cure rate for a stage IV tumor is 82%.
Do germ cell tumors grow fast?
This is a germ cell tumor that is most often malignant, but may also be benign. This tumor most often affects the ovaries or testes, and the lower spine. They are often malignant and grow fast.
What is the most aggressive testicular tumor?
Embryonal carcinoma: present in about 40 percent of tumors and among the most rapidly growing and potentially aggressive tumor types. Embryonal carcinoma can secrete HCG or alpha fetoprotein (AFP). Yolk sac carcinoma: the most common type of tumor in children; responds well to chemotherapy in children and adults.
Is seminoma curable?
Stage I seminomas
These cancers can be cured in nearly all patients. Surgery is done first to remove the testicle and spermatic cord (called a radical inguinal orchiectomy).
Can I live a long life with testicular cancer?
The general 5-year survival rate for men with testicular cancer is 95%. This means that 95 men out of every 100 men diagnosed with testicular cancer will live at least 5 years after diagnosis. The survival rate is higher for people diagnosed with early-stage cancer and lower for those with later-stage cancer.
What causes seminoma cancer?
It’s not clear what causes testicular cancer in most cases. Doctors know that testicular cancer occurs when healthy cells in a testicle become altered. Healthy cells grow and divide in an orderly way to keep your body functioning normally.
What is the function of Sertoli cell?
Sertoli cells are the somatic cells of the testis that are essential for testis formation and spermatogenesis. Sertoli cells facilitate the progression of germ cells to spermatozoa via direct contact and by controlling the environment milieu within the seminiferous tubules.
Are all Sertoli-Leydig cell tumors cancerous?
Sertoli-Leydig cell tumors are rare tumors which account for less than 0.5% of all ovarian tumors. While they can be found in women of all age groups, they are most common in young women. Treatment involves surgery and chemotherapy or radiation if the cancer has spread.