What level of CA125 indicates cancer?
The normal range for CA 125 is 0 to 35 units/ml. While a CA 125 level over 35 may indicate cancer, it does not always mean the person has cancer.
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CA 125 Levels Chart.
CA 125 Levels (units/mL) | Potential Cancer |
---|---|
>35 (high) | Possible cancer. More tests will be needed for a diagnosis. |
What cancer marker is a associated with CA125?
Cancer antigen 125 (CA 125) is the only tumor marker recommended for clinical use in the diagnosis and management of ovarian cancer. The reference range of CA 125 is 0-35 units/mL (0-35 kU/L).
What else can CA125 detect?
A CA 125 test measures the amount of the protein CA 125 (cancer antigen 125) in your blood. A CA 125 test may be used to monitor certain cancers during and after treatment. In some cases, a CA 125 test may be used to look for early signs of ovarian cancer in people with a very high risk of the disease.
Does CA125 blood test detect all cancers?
Blood test (CA125 test)
CA125 is produced by some ovarian cancer cells. A high level of CA125 in your blood could be a sign of ovarian cancer. But a raised CA125 level does not mean you definitely have cancer, as it can also be caused by other conditions such as endometriosis, fibroids and even pregnancy.
Can you be fully cured of ovarian cancer?
Around two in ten women with advanced-stage ovarian cancer are effectively cured and survive at least 12 years after the treatment as per the research. Your response to cancer therapy and chances for a cure depend on the type and the staging of ovarian cancer at the time of diagnosis.
Can stress cause CA125 to rise?
The most popular current theories suggest that CA 125 is synthesized by mesothelial cells in response to stress, which can be either mechanical stress caused by fluid overload, or inflammatory stress instigated by the release of mediators such as TNFα and interleukins [5,6].
Does a high CA 125 always mean cancer?
Does a high CA-125 always mean cancer? No, a high CA-125 does not always mean cancer is present. Generally speaking, the normal range of CA-125 is considered to be 0-35 units/mL, while a level above 35 units/mL is considered to be a high CA-125 level.
What happens if my CA125 is high?
If you are not being treated for ovarian cancer and your results show high CA-125 levels, it can be a sign of cancer. But it may also be a sign of a noncancerous condition, such as: Endometriosis, a condition in which tissue that normally grows inside the uterus also grows outside the uterus.
How accurate is the CA 125 blood test?
Results: Using a CA125 cutoff of 30 U/mL, an overall sensitivity of 94.8% (96.6% specificity) was obtained when comparing malignancies versus healthy postmenopausal controls, whereas a cutoff of 65 U/mL provided a sensitivity of 83.9% (99.6% specificity).
Can CA125 go up and down?
So, CA 125 values can and do fluctuate. Major treatment decisions, such as changing or discontinuing treatment, depend on multiple factors that you and your physician will consider. The trend in your CA 125 values is only one of these factors.
How long does it take for CA 125 results?
Your blood test will be sent to the lab. It will take up to 24 – 48 hours for the results to be ready.