How serious is serous carcinoma?
Uterine papillary serous carcinoma is a serious and often life-threatening disease, and its treatment can be complex.
What is the survival rate of serous carcinoma?
1 Five-year survival rates for early- and advanced-stage serous carcinomas are 75% and 37%, respectively, compared with 86% (p<0.001) and 54% (p<0.001), respectively, for grade 3 endometrioid carcinomas.
Can serous carcinoma be cured?
The most common type of the disease, called endometrioid endometrial carcinoma, is usually diagnosed at an early stage and can often be cured with an operation called a hysterectomy to remove the uterus, sometimes followed by radiation therapy. Uterine serous carcinoma is an aggressive type of endometrial cancer.
What type of cancer is serous carcinoma?
Uterine papillary serous carcinoma, or UPSC, is a rare form of endometrial cancer — cancer of the lining of the uterus. UPSC happens in 5% of uterine cancer cases. It can spread faster and may be more likely to come back after treatment than other types of uterine cancer, even if doctors catch it early.
Is high grade serous carcinoma curable?
Is high grade serous ovarian carcinoma curable? Patients with HGSOC often respond well to treatment, and can experience remission — however, it is common for high grade serous patients to recur over a period of time, with the majority of recurrences occurring within three years.
Where does uterine serous carcinoma spread?
Uterine papillary serous carcinoma (UPSC) is a highly malignant form of endometrial cancer with a high propensity for metastases and recurrences even when there is minimal or no myometrial invasion. It usually metastasizes to the pelvis, retroperitoneal lymph nodes, upper abdomen, and peritoneum.
What is serous carcinoma of female pelvis?
Pelvic serous carcinoma is a general term of any high-grade serous carcinoma in the pelvis, mainly including serous cancers derived from ovary, peritoneum, fallopian tube, endometrium, and cervix.
What is serous in medical terms?
Medical Definition of serous
: of, relating to, producing, or resembling serum especially : having a thin watery constitution a serous exudate.
Is Upsc hereditary?
Background: Uterine papillary serous carcinoma (UPSC) shares common pathologic, genetic, and clinical features with other serous cancers of müllerian origin. The most common histologic type of ovarian tumor associated with BRCA mutations is papillary serous.
What type of ovarian cancer is serous carcinoma?
Most epithelial ovarian/fallopian tube cancers are the serous type, and they are graded as low-grade serous carcinoma (LGSC) or high-grade serous carcinoma (HGSC). These tumors have different genetic alterations and biology.
Is serous cancer hereditary?
Serous uterine cancer is not a feature of any known hereditary cancer syndrome.